July Issue
In a recent human study, caloric restriction dramatically lowered fasting insulin levels and reduced body fat mass. Pinolenic acid, a natural agent that suppresses appetite without stimulatory effects, may help aging adults obtain the multiple benefits of caloric restriction—without hunger.
Reports
What Is Nuclear Factor-Kappa Beta?
Aging people over-express a molecule called nuclear factor-kappa beta, unleashing disease-inducing chronic inflammation. Here we examine NFkB's multiple pathological effects, and how you can safely suppress its influence.
DHA and the Developing Brain
New research indicates that supplementation with the omega-3 fatty acid DHA during and after pregnancy may confer brain-health benefits to young children, improving intelligence, cognition, and visual performance.
Metabolic Syndrome
Most people learn about metabolic syndrome after it has already damaged their arteries and brain cells. Here we show how to determine your risk for metabolic syndrome, and how to guard against this deadly condition.
Longevity Genes and Caloric restriction
In groundbreaking studies, scientists are unraveling how caloric restriction affects the genes that determine longevity, and how manipulating these genes may extend the healthy human life span.
Aspirin
While Life Extension has long recommended aspirin for its cardiovascular benefits, tantalizing new evidence suggests that aspirin may protect against skin cancer, colon cancer, and Alzheimer’s disease.
A4M
Today, A4M trains more than 30,000 physicians and scientists in anti-aging medicine. Thanks to this innovative organization, thousands of doctors are now focused on preventing and reversing diseases associated with aging.
Departments
Eating Ourselves to Death
Caloric restriction not only helps people lose weight and improve lipid levels, but also offers the promise of living a much longer, healthier life. By suppressing appetite and enabling people to consume fewer calories, a remarkable new compound may help aging adults live longer and healthier lives.
Plasma CoQ10 levels predict melanoma progression; vitamins C and E, ibuprofen may prevent Alzheimer's; prehypertension greatly increases cardiovascular risk; early diagnosis critical for surviving prostate cancer; and more.
Familial Hypercholesterolemia
Dr. Sergey Dzugan describes two case studies in which a program of hormonorestoration helped lower cholesterol in two men diagnosed with hypercholesterolemia.