SAMe

S-Adenosyl-Methionine

400 mg, 30 enteric-coated vegetarian tablets Item # 02176

SAMe, 400 mg, 30 enteric-coated vegetarian tablets

Click to Zoom

SAMe, 400 mg, 30 enteric-coated vegetarian tablets

Click to Zoom

Click to Play Video

Thumbnail 1 of 3: SAMe, 400 mg, 30 enteric-coated vegetarian tablets
Thumbnail 2 of 3: SAMe, 400 mg, 30 enteric-coated vegetarian tablets
Thumbnail 3 of 3

SAMe

S-Adenosyl-Methionine

400 mg, 30 enteric-coated vegetarian tablets Item # 02176

Our Best Seller SAMe, or S-Adenosyl-Methionine, benefits many critical metabolic functions in the body. This amazing compound helps maintain a stable mood and supports both joint and liver health.
Non-GMO Vegetarian
Always get the lowest price
and FREE SHIPPING.
Learn More
$27.00
AutoShip Price: $21.60
Save 20%
$0.72/count | 10 - 15 Day Supply

First shipment within 1 business day with FREE standard shipping.

$27.00
Super Sale: $24.30
Save 10%
$0.81 / count | 10 - 15 Day Supply
Buy More, Save More


Couldn't start day without it

Ann, Lakeland, FL

Helps my thinking and my mood. Gives me a feeling of well-being.

Business Owner, Asheville, NC

This product has helped my daughter control her mood swings. It's amazing!

Ben the Octogenarian, Troy, MI

You May Also Like

SAMe

S-Adenosyl-Methionine

400 mg, 30 enteric-coated vegetarian tablets

  • $27.00
  • Sale $24.30
  • Save 10%

$0.81/count | 10 - 15 Day Supply

What Is SAMe?

SAMe participates in many critical metabolic functions by donating methyl groups to other molecules. Methyl groups need to be transferred between compounds in the body to help with things like neurotransmitter signaling and protein function. Laboratory research has shown that SAMe levels appear to decline over time.

SAMe is a compound that has been studied by numerous scientists, researchers and even the U.S. government.

SAMe Benefits

  • Helps maintain stable mood
  • Promotes liver health
  • Supports healthy joint function

SAMe: Subject of Government Research

There is so much research on SAMe that the U.S. Department of Health and Human Services conducted a meticulous evaluation of the evidence. The analysis showed that SAMe has helped maintain stable mood and joint function in several studies.

Life Extension - Why We Do It?

The Best Supplements Science Can Offer

When putting something in your body, you should be confident that you’re getting the nutritional benefits your body deserves. We've been delivering high-quality, science-backed supplements for more than 40 years.

What Matters to You, Matters to Us

We're committed to empowering you to live a healthier life. Whether it’s finding sustainable partners for our ingredients or funding the latest anti-aging research, we're all about your health & wellness.

Highly Recommended

98% of our customers recommend us to family and friends. We're very proud of that because our loved ones matter to us—and we're willing to bet you feel the same way.

Product Transparency

40 years of research dedicated to bringing you premium, scientifically-validated formulations.

S-adenosyl-methionine (SAMe), is made naturally by your body. It participates in many critical metabolic functions by donating methyl groups to other molecules. Methyl groups need to be transferred between compounds in the body to help with things like neurotransmitter signaling and protein function.1,2

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

Serving Size 1 enteric coated vegetarian tablet

Amount Per Serving

S-Adenosyl-Methionine

400 mg

Other ingredients: Cellulose, methacrylic acid copolymer, mannitol, citric acid, stearic acid, silica, hypromellose, glyceryl triacetate, sodium starch glycolate, croscarmellose sodium, calcium carbonate, yellow ochre.

Non-GMO

Dosage and Use
  • Take one (1) tablet one to three times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner.
  • Take with co-factors vitamins B12, B6, and folic acid.
Caution

SAMe should not be taken by those diagnosed with bipolar disorder.

Warnings
  • KEEP OUT OF REACH OF CHILDREN
  • DO NOT EXCEED RECOMMENDED DOSE
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Actual Size

Pill Size: tablet
  1. Am J Clin Nutr. 2002;76(5):1151s-7s.
  2. Annu Rev Biochem. 2016;85:485-514.
  3. J Clin Psychiatry. 2017;78(6):e656-e667.
  4. Am J Med. 1987;83(5a):66-71.
  5. Ann Hepatol. 2013;12(2):183-9.
  6. J Gerontol. 1977;32(4):392-4.
  7. Int J Biochem Cell Biol. 2000;32(4):391-5.
  8. U.S. Department of Health and Human Services. S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease. Accessed May 23, 2019. https://archive.ahrq.gov/clinic/epcsums/samesum.htm

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Full product reviews disclaimer

Mood & Stress
Quiz

Mood & Stress
Quiz

Feeling out of sorts? Find out which mood-boosting nutrients can keep the stress away.

Related Products