| Interventions that can prevent the development of colorectal cancer include screening for adenomas, removal of polyps by endoscopic polypectomy, excision of the large bowel (in FAP) (Munkholm P 2003; Watson P et al 1998), and regular NSAID use (Reeves MJ et al 1996; Giardiello FM et al 1993), in addition to the following dietary interventions: Fiber from bran and cellulose is effective in reducing the risk of colorectal cancer development (Gonzalez CA 2006b); Greenwald P et al 1986). In those with low intake of dietary fiber, doubling of total fiber intake could reduce the risk of colorectal cancer by 40 percent (Bingham S 2006). Fruit fiber consumption, as opposed to vegetable fiber, reduces the risk of colorectal adenomas (Platz EA et al 1997). High-fiber foods include legumes, beans, seeds, nuts, wild rice, and oatmeal. Calcium reduces the growth rate of rectal and colon epithelial cells both directly and by binding bile acids and fatty acids in the stool, resulting in compounds that are less likely to adversely affect the colon (Rozen P et al 1989). Calcium’s beneficial effects may occur only in individuals who have a low level of fat intake (Cats A et al 1995). Oral calcium supplementation reduces benign tumor (adenoma) formation by 19 percent (Baron JA et al 1999) and slightly reduces cell proliferation in the rectum (Cats A et al 1995). Foods such as broccoli, kale, Chinese cabbage, milk, cheese, and yogurt are good sources of calcium. Curcumin is currently being investigated in human clinical trials for the prevention and treatment of colorectal cancer (Jiao Y et al. 2006a). Curcumin may be effective in preventing the development of colon cancer related to APC mutations (Corpet DE et al 2003; Pierre F 2003; Reddy BS et al 1994, 2002). The suggested daily dose is 1.6 grams (Perkins S et al 2002). Curcumin is extracted from turmeric root and is used as a spice in cooking. Multivitamin use reduces the risk of benign tumor (adenoma) formation in high-risk individuals (Whelan RL et al 1999). Vitamins C, E, and A reduce the risk of developing colorectal cancer (Howe GR et al 1992; Newberne PM et al 1990). | Events: Second Annual Life Extension Cruise The second Life Extension Seminar at Sea will be a 7-night cruise on August 29, 2008. This time we will cruise the splendor of the Alaskan wilderness aboard Celebrity’s sumptuous Infinity. You’ll enjoy our Life Extension seminars, one-on-one consultations, a welcome aboard cocktail reception, exceptional personal service, award-winning cuisine, world-famous amenities, accommodations that are the most spacious at sea, and much more. Experience the extraordinary: Celebrity Travel press, such as Condé Nast Traveler, consistently rate Celebrity Cruises as one of the world's finest cruise lines. Celebrity offers an incomparable cruise experience aboard ships of uncompromising style and sophistication. From spectacular dining to indulgent spa treatments, you’ll find countless possibilities to satisfy body and soul. Sleep upon Egyptian cotton linens, enjoy butler service in all suites, or special amenities with Concierge Class staterooms, dine in award-winning restaurants, pay a visit to Fortunes Casino, experience Las Vegas-style shows or a movie in the cinema, be pampered by Celebrity's exclusive AquaSpa programs, and much more. A Celebrity Alaska cruise represents a thoroughly researched and carefully orchestrated collection of spectacular ports of call and exciting shore and land excursions, all connected by routes through some of the area’s most stunning land marine environments. Your ports of call: Seattle, Washington; Sitka, Alaska; Hubbard Glacier (Cruising); Juneau, Alaska; Ketchikan, Alaska; Victoria, British Columbia; Seattle, Washington. For reservations or for more information please call Life Extension Vacations at 800-791-4457 or email reservations@levacations.com. |
