NAD+ plays a critical role in metabolism and the production of cellular energy, but NAD+ levels have been shown to decline with age.^1,2,5 In a randomized controlled trial published in 2019, adults taking 300 mg of nicotinamide riboside (as NIAGEN®) had a 51% increase in blood levels of NAD+ after 2 weeks.⁶

Trans-resveratrol

Resveratrol is a well-known healthy aging nutrient.⁷ Our Resveratrol Elite™ formulas contain trans-resveratrol, the form associated with beneficial biological effects.^8-11 Resveratrol also promotes healthy insulin sensitivity, supports a healthy inflammatory response and has been shown to promote healthy endothelial function for a healthy cardiovascular system.^10,12-14

A more bioavailable resveratrol

We’ve combined resveratrol with galactomannan fibers from fenugreek seeds. This makes our Resveratrol Elite™ formulas up to 10 times more bioavailable.¹⁵ This means that the trans-resveratrol in this product reaches higher levels in your bloodstream and circulates longer than traditional, unformulated resveratrol.

Resveratrol and heart health

One way that resveratrol can promote heart health is by helping to shield your cells from oxidative stress.¹⁶ Resveratrol also promotes endothelial health and function—an essential component of living a long, healthy life.¹⁴

Resveratrol and brain health

At the same time, resveratrol has shown an ability to help the brain and cognition: in a randomized controlled trial, it encouraged healthy neurological function as well as brain blood flow. These are additional ways in which resveratrol can bolster even more essential aspects of healthy aging.¹⁷

Augmenting resveratrol with quercetin

Our formula also delivers quercetin, a phytonutrient that complements resveratrol. In a randomized clinical study, researchers compared the formulated Bio-Quercetin to unformulated quercetin. They found that the quercetin formulated with fenugreek fibers led to serum levels of total quercetin up to 62 times higher than unformulated quercetin, and 18 times higher levels of free (unconjugated) quercetin.¹⁸

Quercetin promotes both cardiovascular and endothelial health and helps maintain healthy blood pressure already within the normal range.^19,20 Quercetin is also a potent inhibitor of oxidative stress and helps promote a healthy inflammatory response.^21,22

Quercetin promotes a healthy immune response in the face of seasonal immune challenges. In a randomized clinical trial, quercetin encouraged a healthy immune response in physically fit older adults.²³

Bio-fisetin

By combining fisetin with fenugreek fibers, we’re able to create a fisetin formula that is up to 25 times more bioavailable.²⁴