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Sex Hormone Binding Globulin Blood Test
Item # LC082016
Measures SHBG levels, a protein that limits sex hormone activity
Sex Hormone Binding Globulin Blood Test
Item # LC082016
Measures SHBG levels, a protein that limits sex hormone activity
This blood test measures the sex hormone binding globulin (SHBG). Low SHBG may lead to ovarian cysts, diabetes and hypothyroidism, while high SHBG may be associated with hyperthyroidism and anorexia. High SHBG levels may also be linked to breast and testicular cancers.
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Testosterone and estradiol circulate in the bloodstream, bound mostly to sex hormone binding globulin (SHBG) and to some degree other blood proteins. Only a small fraction of the sex hormones are unbound, or "free," and thus biologically active and able to enter a cell and activate its receptor. SHBG decreases the active form of the hormone available to the tissues. Thus, bio-availability of sex hormones is influenced by the level of SHBG. High levels of insulin and androgens decrease SHBG level. On the other hand, thyroid hormone, and estrogen increase it. Conditions with low SHBG include ovarian cysts, diabetes, and hypothyroidism. Conditions with high SHBG include pregnancy, hyperthyroidism, and anorexia. There has recently been research to link high SHBG levels with breast and testicular cancer as well. Instructions Fasting is not required for this test. Take all medications as prescribed. If you are supplementing with any hormones, we suggest taking them approximately 2 hours prior to having your blood drawn to see peak levels. Hormones are best drawn between 8-10 AM. |
The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.
Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.
A clinician's order is required for many tests. Where applicable, an independent clinician will review your test request and determine whether to authorize the test, if appropriate. For additional information, see PWNHealth Terms of Service.
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